Weyer's ulnar ray/oligodactyly syndrome is a rare multi-systemic genetic disorder which is characterized by ectrodactyly, ulnar, radial, or fibular ray deficit, and heart, single central incisor, splenic, and renal abnormalities. Cleft lip/palate and hypoplasia of the mandibles have also been observed.[1] It is thought to be inherited in an autosomal recessive pattern.[2] It was first discovered in 1957 by Weyers et al. Only four families worldwide are known to be affected by the disorder.[3][4][5]